Adamax
Also called Adamantyl Semax (as described by sellers)
A modified version of Semax sold online, with basically no published research.
The simple version
- What it does
- It's claimed to boost focus and mood like Semax, but that's unproven.
- How people take it
- No established dose.
- Know this
- There's no published research on it at all, so treat it as an untested chemical.
What it is
Adamax is sold as a changed form of Semax, a Russian nasal-drop medicine, with an extra chemical piece meant to make it last longer and reach the brain more easily. We couldn't find a single published study on Adamax in people or animals. Its exact makeup, purity and effects haven't been confirmed, and it isn't approved anywhere.
How it works
Nobody knows. The idea is that it acts like a longer-lasting Semax, which raises a growth signal for brain cells in rats. That's a guess based on Semax, not something shown for Adamax.
What people use it for
- Focus and mental energy (claimed)
- Mood (claimed)
- A longer-lasting Semax substitute (claimed)
The evidence
Mostly animal studies
We found no published human or animal research on Adamax; everything said about it comes from sellers and users. You can't assume Semax's research carries over, because changing a molecule can change its strength, how long it lasts and its side effects. Treat it as an untested chemical.
How people dose it
No established dose. There isn't enough research or common use to give a typical dose for this one. Be extra careful with anything this unstudied.
Start at the low end, and change one thing at a time. If you take medication or have a health condition, check with a doctor first.
Mix & measure
Set up for a 5 mg vial. Change any number to match yours. New to this? Read how to mix a vial and mg vs mL vs units first.
What you'll need
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Side effects
- Unknown; there are no safety studies
- Users report Semax-like effects: headache, restlessness, poor sleep, irritability
- Nose irritation if used as a spray
Skip it if
- Pregnant or breastfeeding
- History of seizures
- Anxiety, bipolar disorder or other mental health conditions
- If you want something with known safety data (look at studied options first)
Interactions
- Unknown. Be careful with stimulants, antidepressants and seizure medicines.
Get help right away for swelling of the face or throat, trouble breathing, chest pain, or a spreading, hot, red injection site.
Storage & legal
Storage
Powder: fridge or freezer. Once mixed: fridge, use within about 2–4 weeks.
Legal status
FDA: Not approved. Not legally sold for human use in the US.
Sport (WADA): Not approved by any health authority, so it falls under WADA's S0 (non-approved substances): prohibited at all times.
Common questions
Is Adamax just a stronger Semax?
That's how it's marketed, but no published study has tested it. And if it's stronger or lasts longer, any side effects could be too.
Why is there no dose listed?
Because there's no research to base one on and no agreed range among users. We'd rather show nothing than guess.
How do I know what is actually in the vial?
You can't without independent lab testing. With an unstudied compound like this, that risk is higher than usual.
Sources
- Dolotov OV, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res. 2006;1117(1):54-60. (Parent compound; no Adamax studies found.) PubMed 16996037
- Gusev EI, et al. The efficacy of semax in the treatment of patients at different stages of ischemic stroke. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(3. Vyp. 2):61-68. (Parent compound.) PubMed 29798983
- World Anti-Doping Agency. The Prohibited List (S0 Non-approved substances). Source
Last checked 2026-10