Peptide Safely
39 guides

Every peptide, explained

What each one does, how people dose it, how to mix it, and how strong the evidence is.

Mostly animal studies

5-Amino-1MQ

Small-molecule NNMT inhibitor (not a peptide)

A small molecule that cut fat in obese mice. It hasn't been tested in people.

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Mostly animal studies

Adamax

Modified Semax analog (unstudied)

A modified version of Semax sold online, with basically no published research.

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Some human studies

AOD-9604

Modified growth hormone fragment

A piece of growth hormone meant to burn fat that failed its biggest human trial.

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Some human studies

ARA-290

Non-blood-boosting EPO-derived peptide

Part of the EPO hormone, built to ease nerve pain without raising red blood cells.

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Mostly animal studies

BPC-157

Gastric pentadecapeptide

A lab-made piece of a stomach protein that helped rats heal, barely tested in people.

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Some human studies

Cagrilintide

Long-acting amylin analogue

An experimental weekly shot copying a fullness hormone, tested with semaglutide for bigger weight loss.

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Mostly animal studies

CJC-1295 (No DAC)

GHRH analog (growth hormone-releasing hormone)

A short-acting signal that tells your pituitary gland to release your own growth hormone.

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Some human studies

DSIP

Neuropeptide (nonapeptide)

A peptide first found in rabbits, hoped to deepen sleep, with mixed results in people.

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Mostly animal studies

Epitalon

Synthetic pineal tetrapeptide

A tiny peptide promoted for healthy aging, based mostly on Russian animal and cell studies.

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Some human studies

GHK-Cu

Copper-binding tripeptide

A natural copper peptide long used in skin creams; injecting it is new and untested.

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Some human studies

Glutathione

Tripeptide antioxidant (3 amino acids)

Your body's main built-in antioxidant, sold as pills, shots and drips for skin and 'detox'.

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Mostly animal studies

Humanin

Mitochondrial-derived peptide

A protective peptide your mitochondria make, studied in labs for aging, brain and heart.

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Mostly animal studies

IGF-1 LR3

Modified insulin-like growth factor 1

A lab-tweaked version of IGF-1, the growth factor that does much of growth hormone's work.

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Some human studies

Ipamorelin

Growth hormone secretagogue (ghrelin mimic)

A peptide that copies the hunger hormone ghrelin to trigger a burst of growth hormone.

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Some human studies

Kisspeptin-10

Reproductive neuropeptide (KISS1R agonist)

The short active piece of a natural hormone that switches on your sex-hormone chain.

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Mostly animal studies

KPV

Anti-inflammatory tripeptide

A tiny three-amino-acid peptide that calmed gut inflammation in mice; never tested in people.

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Some human studies

LL-37

Human antimicrobial peptide (cathelicidin)

A germ-fighting peptide your body makes; in people, only tested as a wound gel.

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FDA-approved

Melanotan I

Melanocortin-1 receptor agonist (13 amino acids)

A lab-made tanning hormone, approved as an implant for a rare light-sensitivity disease.

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Some human studies

Melanotan II

Non-selective melanocortin receptor agonist (cyclic 7 amino acids)

Unapproved tanning shot that also raises sex drive and cuts appetite, with real skin risks.

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Mostly animal studies

MOTS-c

Mitochondrial-derived peptide (16 amino acids)

A tiny peptide your mitochondria make, studied in mice for blood sugar, weight and endurance.

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Some human studies

NAD+

Coenzyme (not a peptide)

A helper molecule your cells use to make energy. Levels drop with age.

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Mostly animal studies

PEG-MGF

Pegylated IGF-1 splice-variant peptide

A longer-lasting lab copy of a muscle signal, with almost no proof in people.

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FDA-approved

PT-141

Melanocortin receptor agonist (cyclic 7 amino acids)

An as-needed shot for low desire that works in the brain, not on blood flow.

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Some human studies

Retatrutide

Triple GIP, GLP-1 and glucagon receptor agonist

An experimental weekly shot copying three hormones, with the biggest trial weight loss so far.

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Some human studies

Selank

Tuftsin-analog heptapeptide

A Russian nasal spray for anxiety, said to calm you without making you sleepy.

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FDA-approved

Semaglutide

GLP-1 receptor agonist

A weekly shot that turns down hunger so most people eat less and lose weight.

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Some human studies

Semax

ACTH-fragment heptapeptide

Russian nasal drops built from part of a stress hormone, used there after strokes.

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Some human studies

Sermorelin

GHRH analog (growth hormone-releasing hormone)

A copy of your brain's own signal to release growth hormone, once FDA-approved for kids.

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FDA-approved

SS-31

Mitochondria-targeting tetrapeptide

A tiny peptide that targets your cells' energy makers, approved for one rare disease.

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Mostly animal studies

TB-500

Synthetic thymosin beta-4 peptide

A lab copy of part of a repair protein, popular for injuries but barely tested.

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FDA-approved

Tesamorelin

GHRH analog (growth hormone-releasing hormone)

An FDA-approved shot that shrinks deep belly fat in people with HIV.

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Some human studies

Tesofensine

Triple monoamine reuptake inhibitor (small molecule, not a peptide)

An experimental daily pill that curbs appetite but speeds up your heart.

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Some human studies

Thymosin Alpha-1

Thymic immune-modulating peptide

An immune peptide sold as a prescription drug in many countries, but not the US.

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FDA-approved

Tirzepatide

Dual GIP and GLP-1 receptor agonist

A weekly shot copying two gut hormones; it usually cuts appetite more than older drugs.

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Mostly animal studies

BPC-157 + TB-500

Two-peptide recovery blend · Blend

Two popular healing peptides in one vial, nicknamed the Wolverine stack.

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Some human studies

CJC-1295 (no DAC) + Ipamorelin

Growth-hormone releasing blend · Blend

Two peptides in one vial that get your body to release more growth hormone.

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Mostly animal studies

KLOW

Four-peptide repair blend · Blend

Four peptides for repair and calming inflammation, packed into one vial.

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Some human studies

Retatrutide + Cagrilintide

Weekly weight-loss blend (triple agonist + amylin analog) · Blend

Two experimental weekly weight-loss shots in one vial, never tested together in people.

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Some human studies

Tesamorelin + CJC-1295 (no DAC) + Ipamorelin

Three-peptide growth-hormone releasing blend · Blend

Three peptides in one vial that push your own growth hormone release. No standard ratio.

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