Peptide Safely
Some human studiesMuscle gainBlend

CJC-1295 (no DAC) + Ipamorelin

Also called CJC/Ipa, Mod GRF 1-29 + Ipamorelin, CJC-Ipamorelin blend

Two peptides in one vial that get your body to release more growth hormone.

Get CJC-1295 (no DAC) + Ipamorelin ↗Plan my suppliesTested by Vertex Labs. We may earn a commission.
Typical dose200–600 µg of blend (100–300 µg of each)
How oftenOnce a day, sometimes twice
Half-lifeCJC-1295 (no DAC): about 30 minutes. Ipamorelin: about 2 hours.
Vial sizes10 mg

The simple version

What it does
It gets your body to release bigger bursts of its own growth hormone.
How people take it
200–600 µg of blend as a shot under the skin, once a day at bedtime on an empty stomach.
Know this
No trial has shown this blend improves fat, muscle or sleep in healthy adults.

What's inside

What it is

This is a premixed vial of CJC-1295 without DAC (also called Mod GRF 1-29) and ipamorelin, usually 5 mg of each (10 mg total), and it's the most common growth hormone peptide blend. It doesn't contain growth hormone. Instead, it tells your pituitary, a small gland under your brain, to release more of its own.

How it works

Your body uses two signals for growth hormone: one says release, and the other makes each release bigger. CJC-1295 copies the first and ipamorelin copies the second, so using both tends to give a bigger burst than either alone. People like ipamorelin because in animal studies it raised growth hormone without much rise in two other hormones, cortisol and prolactin.

What people use it for

  • Sleep quality
  • Recovery from training
  • Body shape (less fat, more lean muscle)
  • Skin and general wellbeing

The evidence

Some human studies

There are small human studies of each part, but none of this blend. The best-known human CJC-1295 studies used a different, week-long version (with DAC), the short-acting version in this blend has very little human data, and ipamorelin was tested in people only for gut recovery after surgery, not fitness or anti-aging. No trial has shown this blend improves body fat, muscle or sleep in healthy adults.

How people dose it

Label doseFDA labelTrial doseclinical trialsReportedcommon use, untested

Standard

Reported
Dose
200–600 µg of blend (100–300 µg of each)
How often
Once a day, sometimes twice
When
Bedtime, on an empty stomach (at least 2 hours after food)
Cycle
8–12 weeks, often 5 days on and 2 days off, then a break of similar length
Route
Subcutaneous injection

Why: Your biggest natural growth hormone burst happens early in sleep, so a bedtime dose adds to it. Food, especially carbs and fat, dulls the release, so people take it on an empty stomach. Both parts wear off fast, so the effect fits one burst. Example: add 2 mL of bacteriostatic water to a 10 mg vial. That makes 5 mg/mL of blend. A 200 µg dose (100 µg of each) is 0.04 mL, or 4 units on a U-100 insulin syringe.

Low/starter

Reported
Dose
100–200 µg of blend (50–100 µg of each)
How often
Once a day
When
Bedtime, empty stomach
Cycle
First 1–2 weeks
Route
Subcutaneous injection

Why: Starting low lets you watch for water retention, tingling hands or flushing before you go higher. With the 2 mL mix above, 100 µg of blend is 0.02 mL, or 2 units.

Start at the low end, and change one thing at a time. If you take medication or have a health condition, check with a doctor first.

Mix & measure

Set up for a 10 mg vial. Change any number to match yours. New to this? Read how to mix a vial and mg vs mL vs units first.

mg
mL
–

Plan your supplies

Pick your dose and how long you'll run it. We'll count what you need.

µg
–
We may earn a commission from these links. Counts include one syringe and two swabs per dose.

Stay safe

Side effects

  • Flushing or warmth right after the shot
  • Redness where you inject
  • Headache
  • Water retention or puffiness
  • Tingling or numb hands
  • Achy joints
  • Hunger
  • Higher blood sugar with long use
  • Side effects of both parts add together

Skip it if

  • Any cancer now or in the past (growth hormone and IGF-1, a growth signal it raises, can feed cell growth)
  • Diabetes or prediabetes, unless a doctor is watching your blood sugar
  • Pregnant or breastfeeding
  • Under 18
  • Pituitary disease or past pituitary surgery
  • Competing in drug-tested sports

Interactions

  • Insulin and diabetes meds (growth hormone raises blood sugar)
  • Steroid meds like prednisone can weaken the effect
  • Don't combine with growth hormone itself without a doctor

Get help right away for swelling of the face or throat, trouble breathing, chest pain, or a spreading, hot, red injection site.

Storage & legal

Storage

Powder: fridge or freezer. Mixed: fridge, use within about 4 weeks.

Legal status

FDA: Not approved. FDA has listed CJC-1295 and ipamorelin among bulk substances with safety concerns for compounding (2023).

Sport (WADA): Prohibited (S2: growth hormone releasing factors and secretagogues).

Often paired with

Common questions

Is this the same as the CJC-1295 in studies?

Mostly no. The main human studies used CJC-1295 with DAC, which lasts about a week. This blend uses the no-DAC version, which lasts minutes and gives a short burst instead.

Why one vial instead of two?

Fewer shots and less mixing. The catch is the ratio is fixed, so you can't raise ipamorelin without raising CJC-1295 too.

Will it work like taking growth hormone?

No. It only boosts your own release, which is much smaller and still controlled by your body. Any effects build slowly over weeks.

Sources

  1. Teichman SL, et al. Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults. J Clin Endocrinol Metab. 2006;91(3):799-805. PubMed 16352683
  2. Ionescu M, Frohman LA. Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog. J Clin Endocrinol Metab. 2006;91(12):4792-7. PubMed 17018654
  3. Raun K, et al. Ipamorelin, the first selective growth hormone secretagogue. Eur J Endocrinol. 1998;139(5):552-61. PubMed 9849822
  4. Dominikowski A, et al. The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration. Front Endocrinol (Lausanne). 2026;17:1822475. PubMed 42395176

Last checked 2026-10